The impact of neuropsychological functioning and coping style on perceived stress in individuals with first-episode psychosis and healthy controls (2024)

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Persons with first episode psychosis have distinct profiles of social cognition and metacognition

2021 •

esther pousa

Subjects with first-episode psychosis experience substantial deficits in social cognition and metacognition. Although previous studies have investigated the role of profiles of individuals in social cognition and metacognition in chronic schizophrenia, profiling subjects with first-episode psychosis in both domains remains to be investigated. We used latent profile analysis to derive profiles of the abilities in 174 persons with first-episode psychosis using the Beck’s Cognitive Insight Scale, the Faces Test, the Hinting Task, the Internal, Personal and Situational Attributions Questionnaire, and the Beads Task. Participants received a clinical assessment and a neuropsychological assessment. The best-fitting model was selected according to the Bayesian information criterion (BIC). We assessed the importance of the variables via a classification tree (CART). We derived three clusters with distinct profiles. The first profile (33.3%) comprised individuals with low social cognition. Th...

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The relative contribution of neurocognition and social cognition to 6-month vocational outcomes following Individual Placement and Support in first-episode psychosis

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European Psychiatry

European Psychiatric Association guidance on assessment of cognitive impairment in schizophrenia

Antonio Vita

Background Impairment in a wide range of cognitive abilities has been consistently reported in individuals with schizophrenia. Both neurocognitive and social cognitive deficits are thought to underlie severe functional disabilities associated with schizophrenia. Despite the key role in schizophrenia outcome, cognition is still poorly assessed in both research and clinical settings. Methods In this guidance paper, we provide a systematic review of the scientific literature and elaborate several recommendations for the assessment of cognitive functions in schizophrenia both in research settings and in real-world clinical practice. Results Expert consensus and systematic reviews provided guidance for the optimal assessment of cognitive functions in schizophrenia. Based on the reviewed evidence, we recommend a comprehensive and systematic assessment of neurocognitive and social cognitive domains in schizophrenia, in all phases of the disorder, as well as in subjects at risk to develop p...

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European Archives of Psychiatry and Clinical Neuroscience

Males and females with first episode psychosis present distinct profiles of social cognition and metacognition

esther pousa

Deficits in social cognition and metacognition impact the course of psychosis. Sex differences in social cognition and metacognition could explain heterogeneity in psychosis. 174 (58 females) patients with first-episode psychosis completed a clinical, neuropsychological, social cognitive, and metacognitive assessment. Subsequent latent profile analysis split by sex yielded two clusters common to both sexes (a hom*ogeneous group, 53% and 79.3%, and an Indecisive group, 18.3% and 8.6% of males and females, respectively), a specific male profile characterized by presenting jumping to conclusions (28.7%) and a specific female profile characterized by cognitive biases (12.1%). Males and females in the hom*ogeneous profile seem to have a more benign course of illness. Males with jumping to conclusions had more clinical symptoms and more neuropsychological deficits. Females with cognitive biases were younger and had lower self-esteem. These results suggest that males and females may benefit ...

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Nikie Korver

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Insight and frontal cortical function in schizophrenia: A review

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Social functioning and social cognition in at-risk and first episode psychosis

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Paul Kennedy

Reduced social functioning is a key characteristic of the psychosis continuum. However, it is currently unclear how effective a range of psychological interventions are in improving social functioning in at risk mental states (ARMS) and first episode psychosis (FEP) populations. One treatment target that has received increased interest is social cognitive function. However, there has not yet been a comprehensive analysis of the literature investigating the relationship between social cognition, social functioning, and psychotic symptomatology. To this end we conducted a systematic review and meta-analysis to determine the effectiveness of psychological interventions on social functioning, and to determine the nature of relationship between social cognition, social functioning and psychotic symptoms in ARMS and FEP. Our systematic review demonstrated that CBT, multicomponent and service level interventions have efficacy in FEP, whilst there is currently no evidence that CBT, and limi...

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Schizophrenia Bulletin

Trait and State Attributes of Insight in First Episodes of Early-Onset Schizophrenia and Other Psychoses: A 2-Year Longitudinal Study

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David Fraguas

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Journal of Clinical Medicine

Exploring Risk and Resilient Profiles for Functional Impairment and Baseline Predictors in a 2-Year Follow-Up First-Episode Psychosis Cohort Using Latent Class Growth Analysis

Silvia Amoretti

Being able to predict functional outcomes after First-Episode Psychosis (FEP) is a major goal in psychiatry. Thus, we aimed to identify trajectories of psychosocial functioning in a FEP cohort followed-up for 2 years in order to find premorbid/baseline predictors for each trajectory. Additionally, we explored diagnosis distribution within the different trajectories. A total of 261 adults with FEP were included. Latent class growth analysis identified four distinct trajectories: Mild impairment-Improving trajectory (Mi-I) (38.31% of the sample), Moderate impairment-Stable trajectory (Mo-S) (18.39%), Severe impairment-Improving trajectory (Se-I) (12.26%), and Severe impairment-Stable trajectory (Se-S) (31.03%). Participants in the Mi-I trajectory were more likely to have higher parental socioeconomic status, less severe baseline depressive and negative symptoms, and better premorbid adjustment than individuals in the Se-S trajectory. Participants in the Se-I trajectory were more likel...

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A prospective comparison of two models of cannabis use and psychotic relapse in early psychosis

Sharon Dawe, David Kavanagh

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The impact of neuropsychological functioning and coping style on perceived stress in individuals with first-episode psychosis and healthy controls (2024)

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